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Localized tissue anemia as a result of obstruction of the blood supply or to vasoconstriction.



a local deficiency of blood; insufficient blood in an organ or tissue because of the narrowing or complete occlusion of the lumen of an afferent artery.

Transitory ischemia (like hyperemia) may result from physiological regulation of the blood supply, such as in reflex spasm of an artery caused by a mental factor (fright); the influence of pain, cold, chemical substances (epinephrine, ergotin), and biological stimuli (bacteria, toxins); the obstruction of an artery by a thrombus or embolus; constriction of the lumen of a blood vessel in connection with an atherosclerotic or inflammatory process in the wall; or compression of an artery by a tumor, scar, or foreign body. The aftereffects of ischemia depend on the degree of disruption of the blood flow, the rate of development and duration of the ischemia, the sensitivity of the tissue to oxygen deficiency, and the general condition of the body. Ischemia may end in complete restoration of the structure and function of the affected organ or tissue, but it also may lead to necrosis (infarct). The central nervous system and heart muscle are particularly sensitive to ischemia.


References in periodicals archive ?
com adds "Myocardial Ischemia - Pipeline Review, H1 2015" therapeutic market research report provides an overview of the Myocardial Ischemia's therapeutic pipeline
It has been supposed that green tea polyphenols (GTPs) have neuroprotective effects on brain damage after brain ischemia in animal experiments.
Each scoring system was evaluated for their associations with ischemia time (primary outcome) and perioperative change in serum creatinine concentration (secondary outcome).
Another surprising fact she highlighted is how cardiologists manage patients found to have moderate or severe inducible ischemia.
Van Kooten F, Ciabattoni G, Koudstaal PJ, Dippel DW, Patrono C (1999) Increased platelet activation in the chronic phase after cerebral ischemia and intracerebral hemorrhage.
Coverage of the Myocardial Ischemia pipeline on the basis of route of administration and molecule type.
Robert Dominici, CEO of Ischemia, added, "We are delighted to have Ischemia's products and patents become part of the Inverness medical diagnostic strategy and organization.
Coverage of the Ischemia pipeline on the basis of route of administration and molecule type.
A snapshot of the global therapeutic scenario for Critical Limb Ischemia.
Coronary computed tomographic angiography is a noninvasive anatomic test for diagnosis of coronary stenosis [narrowing of a blood vessel] that does not determine whether a stenosis causes ischemia [inadequate blood supply], explained researchers.
Cerebral ischemia and subsequent reperfusion caused a substantial increase in cerebral tissue conjugated diene.
Conclusion: In contrast to regional subendocardial ischemia, global subendocardial ischemia can explain ST depression in our model.