isocyanide


Also found in: Dictionary, Medical, Wikipedia.

isocyanide

[¦ī·sō′sī·ə‚nīd]
(organic chemistry)
A compound with the general formula RN≡C in which the hydrogen of a hydrocarbon has been replaced by the ‒N≡C group.
Mentioned in ?
References in periodicals archive ?
The chemistry of the isocyanides is profoundly different from the rest of organic chemistry, because the functional group of the isocyanides is the only one that contains a divalent carbon atom [C.
In the usual organic chemistry only a few MCRs are known, and each reaction produces compounds with a similar skeleton and only different substituents, whereas in the chemistry of the isocyanides a much greater variation of MCRs is known.
Since 1958 when Ugi and his co-workers introduced new methods of preparing the isocyanides by dehydrating formylamines [1-3] the isocyanides are well available.
In 1959 Ugi and co-workers introduced the U-4CR of the isocyanides [1, 4, 5], which is since 1962 quoted as the Ugi reaction [5].
2000, 112, 3300-3344; Multicomponent reactions with isocyanides.
4 mmol of the isocyanide 4a-c were added together with the needed amount of Zn[Cl.
on April 2, 1995; Do: Molecular diversity via a convertible isocyanide in the four component condensation.
In 1959 the four component reaction of amines, carbonyl compounds, acids, and isocyanides was introduced [19], which is now one of the most often used chemical reactions.
Since 1995 the chemistry of the MCRs and the libraries of the isocyanides are the most often used reactions of forming chemical products and their libraries [9] in order to find thus new desirable products with pharmaceutical potential.
Subsequently these were reacted by U-4CRs with acid components 3a-i and the isocyanides 4a-c at -42[degrees]C to + 20[degrees]C in methanol and in some cases Zn[Cl.