isodisomy


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isodisomy

[‚ī·sə‚dī′sō·mē]
(genetics)
A type of uniparental disomy in which two copies of the same chromosome are inherited from one parent, with resultant homozygosity at all gene loci on the chromosome.
References in periodicals archive ?
The inheritance of two copies of an identical chromosome is known as isodisomy, and results in whole chromosome ROH.
However, the presence of the same paternal haploid complement in both cell lines suggests paternal uniparental isodisomy and involvement of only a single egg and sperm nucleus.
In one patient with classic TIOD, a homozygous deletion in exon 14 appeared to have resulted from partial maternal isodisomy of the short arm of chromosome 2 carrying the defective TPO gene (Bakker et al.