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isoelectric point

   Also found in: Dictionary/thesaurus, Medical, Legal, Financial, Acronyms, Wikipedia, Hutchinson 0.02 sec.
isoelectric point [¦ī·sō·i′lek·trik ′pȯint]
(physical chemistry)
The pH value of the dispersion medium of a colloidal suspension at which the colloidal particles do not move in an electric field.


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Isoelectric focusing showed that AX476 produced a [beta]-lactamase with an isoelectric point of 7.
Separation can be done simply at the whole-protein level using two-dimensional gel electrophoresis; this technique separates molecules by molecular weight and isoelectric point (the pH at which a molecule carries no net electrical charge).
The mixed-mode sorbents can distinguish proteins that have similar or very close isoelectric points, a separation that cannot be achieved with a single ion exchange step.
 
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