isogenic


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isogenic

[‚ī·sə·jə′nē·ik]
(genetics)
Having the same genotype, as all organisms of an inbred strain.
(immunology)
Referring to cells, tissues, or organs used in transplantation that originate in identical species.
References in periodicals archive ?
Furthermore, estimates were lower by an order of magnitude compared with estimates derived from previous reports based on an isogenic mouse model.
2004, "Characterization of biosurfactant production by Serratia marcescens SS-1 and its isogenic strain SMDR defective in SpnR, a quorum sensing LuxR family protein," Biotechnol.
Morphological and fertility responses in isogenic triploid and hexaploid pearl millet x napier-grass hybrids.
Four years of Monsanto research trials showed a yield advantage of 7% to 11% for Roundup Ready 2 Yield soybeans compared with Roundup Ready soybeans of near isogenic lines, the company reports.
Isogenic cell-line pairs, where one cell line contains a genetic alteration or mutation of interest and the other contains the normal gene, represent cell-based models that portray specific human diseases in the context of their matched genetic backgrounds.
0 which is isogenic to wild type Shigella only the icsA::phoA fusion gene has replaced wild type icsA.
Lexicon's positive-negative selection and isogenic DNA technologies are efficient methods of targeting genes for the generation of knockout mice, which are used to determine the role of specific genes in mammalian disease and physiology.
AFLP fingerprints can be used to distinguish even very closely related organisms, including near isogenic lines.
coli which includes the wild-type strain, AJW678, and a set of isogenic mutants in varies cell surface organelle or regulator genes.
elegans is a very attractive system because developmental patterning is highly stereotypical and animals are isogenic, thereby allowing precise control of the genetic background.
For example, assays could be developed and validated in sandy and clay soils, different sediments, and water types, with isogenic pairs of the model organism inoculated into the matrix of choice and subjected to a titration of the selective agent to sufficiently high dilution.