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Our previous studies also confirmed that sugar is a signal molecule that induces gene expression of key enzymes including chalcone isomerase (CHI), flavonols synthetase (FLS) and anthocyanidin synthase (ANS) involved in flavonoid biosynthesis in ginkgo.
The now completed acquisition includes approximately 5% further of the shares in Isomerase through a 550 000 GBP cash payment.
The report provides a snapshot of the global therapeutic landscape for Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor or L-Dopachrome Isomerase or MIF or EC 5.
Additionally, decreased NO bioavailability due to peroxynitrite formation leads to lower extents of PDI reacting with available NO and/or less NO inhibiting PDI isomerase activity, which would shift the enzyme's activity to proaggregatory pathways (Figure 2).
Glucose phosphate isomerase is an enzyme which reversibly catalyses transformation of glucose 6 phosphate and fructose 6 phosphate to each other which is the second step of anaerobic glycolysis in the Embden Meyerhof pathway.
Optimization of operating temperature for continuous glucose isomerase reactor system.
The essential mitotic peptidyl-prolyl isomerase Pinl binds and regulates mitosis-specific phosphoproteins.
Autoantigens defined by experimental serum and B-cell analysis in RA syndromes in animals and humans (10) Type/nature Specificity Autoantigen Citrulline-containing peptide Keratin Perinuclear factor Savoy antigen Filaggrin Human leukocyte antigen Calpastatin Immunoglobulin (rheumatoid factor) Calreticulin Antineutrophil cytoplasmic antigen Antinuclear antibody Immunoglobulin heavy-chain protein / p68 Heteronuclear ribonucleoprotein A2 (RA33) Glucose-6-phosphate isomerase Cartilage (organ Collagen type II specific) Chondrocyte antigen 65 Large aggregating chondroitin sulfate proteoglycan (aggrecan) Human chondrocyte glycoprotein 39 Cartilage oligomeric matrix protein Non-autoantigens Bacterial heat shock protein
The study focused on protein disulfide isomerase (PDI), which is found in all cells.
As shown in the histogram of Figure 2, one protein from the SwissProt protein database matches the peptides of the mgf file with higher confidence than any other--in this case, triosephosphate isomerase (TPI) has a protein score of 253, well above the probability cut-off (green shaded box) of 28 (P < 0.