Classical work by Bloch, Cornforth and Lynen on mammalian and yeast cells in the 1950s culminated in the elucidation of the mevalonate pathway for the biosynthesis of the universal
isoprenoid precursors, isopentenyl diphosphate (IPP) (7) and dimethylallyl diphosphate (DMAPP) (8) via acetyl-CoA (11), 3-hydroxy-3-methylglutaryl-CoA (10) and 5-diphospho-mevalonate (9) (for review, see Qureshi and Porter, 1981; Bach, 1995; Bloch, 1992; Bochar et al.
Benzophenones and xanthones with
isoprenoid groups from Cudrania cochinchinensis.
The origin of viruses, prokaryotes, eukaryotes, primates and humans from the initial
isoprenoid organism derived actinidic archaea is discussed.
25] regular
isoprenoids are absent or are present in traces only, 8-methyl-2-methyl-2-(4,8,12-tri-methyltridecyl) chroman is absent, extended homohopanes above [C.
DEINOCHEM first targets
isoprenoids, which constitute one of the families of the most diverse natural substances (over 22,000
isoprenoid compounds are listed to date).
Network analysis of the MVA and MEP pathways for
isoprenoid synthesis.
The methodology applied to estimate
isoprenoid emissions on a regional scale contributes to the understanding of carbon exchange between biosphere and atmosphere.
The intermediates GPP, FPP and GGPP are catalyzed by the corresponding terpene synthase to produce all
isoprenoid end products (Patra et al.
Fatty-acid synthesis was significantly inhibited only at the highest dose of G, whereas nonsaponifiable-lipid synthesis was substantially reduced at all three doses of the
isoprenoid (Fig.
10], Decaprenyl diphosphate synthase, Farnesyl diphosphate,
IsoprenoidSeveral candidate plant growth controllers are known but the
isoprenoid compound abscisic acid (ABA; 5-(1-Hydroxy-2,6,6-trimethyl-4oxo-2-cyclohexen-1-yl)-3-methyl-2,4-pentanedienoic acid) seemed a particularly strong candidate for the hypothesized growth inhibiting substance as it is a known plant growth inhibitor.
Distribution of the mevalonate and glyceraldehydes phosphate/pyruvate pathways for
isoprenoid biosynthesis in unicellular algae and the cyanobacterium Synechocystis PCC 6714.