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isoproterenol |
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isoproterenol [‚ī·sə‚prōd·ə′rē‚nȯl] (pharmacology) C11H17NO3A sympathomimetic amine used as a bronchodilator. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Typically, isoproterenol is titrated to maintain a heart rate of about 110 beats per minute for the first 72 hours and is then tapered off. There are many variations on this story: isoproterenol inhalers, used to relieve asthma, caused 3500 deaths in England and Wales in the sixties; practolol, an anti-hyper-intensive, caused a number of cases of permanent or near-permanent blindness in England in the seventies. On the fifth day, scientists injected each subject with a localized microdose of a substance that causes vessel contriction, followed by a small dose of isoproterenol, an adrenaline-like substance that causes dilation. |
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