hydralazine

(redirected from isosorbide dinitrate)
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Related to isosorbide dinitrate: prochlorperazine, Isosorbide mononitrate

hydralazine

[hī′dral·ə‚zēn]
(pharmacology)
C8H8N4 An antihypertensive drug; used as the hydrochloride salt.
References in periodicals archive ?
Group-I (Study group, n=60): in which only propofol infusion used during rewarming and Group-II (control Group, n=60) in which isosorbide dinitrate and propofol infusion combination was used during rewarming.
He added: "Work by the company to treat and safely remove from the site the pharmaceutical material, Isosorbide Dinitrate, (ISDN Pure), which had explosive properties, started at the beginning of this year and was completed recently.
The 80 rats were randomly divided into 6 groups: normal control (Control), sham operation (Sham), injured (AMI), PE low dose (AMI + PE-L), PE high dose (AMI + PE-H) and isosorbide dinitrate positive control (AMI + isosorbide).
Augmentation of the vasodilatory effects of isosorbide dinitrate by phosphodiesterase inhibitors (e.
Don't use PDE5 inhibitors if you take nitrates--drugs such as nitroglycerine, isosorbide dinitrate (Isordil) and isosorbide mononitrate (Imdur) used to treat angina-because the combination can cause a dangerous drop in blood pressure and lead to heart attack or stroke.
The study, "Combination of Isosorbide Dinitrate and Hydralazine in Blacks with Heart Failure (A-HeFT)," was published in The New England Journal of Medicine, where the addition of isosorbide dinitrate plus hydralazine to standard therapy for heart failure was effective in decreasing mortality rates in black patients with New York Heart Association class III or IV heart failure.
Less than a month later, NitroMed went public, raising $66 million (even though isosorbide dinitrate and hydralazine are available separately in generic formulations, making it possible to closely approximate NitroMed's combination at a cost of about 44 cents per dose).
The drug is BiDil, an experimental combination of two already approved drugs, isosorbide dinitrate (Isordil), which provides nitric oxide, and hydralazine (Apresoline), which helps the body better use nitric oxide.
The purpose of this study was to determine the effect of isosorbide dinitrate 0.
Cohn of the University of Minnesota Medical School in Minneapolis and his colleagues present data suggesting that enalapril provides better protection for people with mild to moderate heart failure than a combination of hydralazine and isosorbide dinitrate, two other blood-vessel dilators.
Pantaprazole 40Mg 3,000,Tab Telmisartan +Hydrochlorothi Azide 5,000,Tab-Telmisartan+Amlodipine 3,000,Tab Isosorbide Dinitrate 10 300,Tab-Clopidogrel 75Mg 1,000,Tab.
A substantial quantity of isosorbide dinitrate was found during a joint inspection at Euticals Limited by the Health and Safety Executive (HSE) and Environment Agency Wales in November, last year causing work to stop.