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isochron
(redirected from isosorbide dinitrate)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
isochron [′ī·sə‚krän]
(geochemistry)
A line on a graph defined by data for rocks of the same age with the same initial lead isotopic composition, the slope of which is proportional to the age. Also known as geochron.


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A study comparing the formulations of isosorbide dinitrate (ISDN) and hydralazine (HYD) used in V-HeFT I and V-HeFT II, and BiDil, the proprietary fixed dose combination, used in the African American Heart Failure Trial (A-HeFT) demonstrated no bioequivalence.
One example of a medicine targeted at racial categories is BiDil (fixed-dose isosorbide dinitrate and hydralazine), an antihypertensive drug that was approved specifically for use in blacks.
1-15) The study, "Combination of Isosorbide Dinitrate and Hydralazine in Blacks with Heart Failure (A-HeFT)," was published in The New England Journal of Medicine, where the addition of isosorbide dinitrate plus hydralazine to standard therapy for heart failure was effective in decreasing mortality rates in black patients with New York Heart Association class III or IV heart failure.
 
 
 
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