isosterism


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isosterism

[ī′säs·tə‚riz·əm]
(physical chemistry)
A similarity in the physical properties of ions, compounds, or elements, as a result of electron arrangements that are identical or similar.
References in periodicals archive ?
Isosterism or bioisosterism is one of the approaches most frequently used in the design of new molecules [1].
In the current review, a chronological order study of bioisosterism and crucial role of isosterism or bioisostreism has been investigated with clear 2D and 3D chemical structures illustration of drugs of therapeutic importance.
Analogous compounds may be obtained through homologation, chain branching of aliphatic side chains, altering ring substitutions and substituents, ring-chain transformations, and isosterism.