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isotope dilution |
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isotope dilution [′ī·sə‚tōp də‚lü·shən] (nucleonics) The introduction of a radioisotope into stable isotopes of an element in order to make volume, mass, and age measurements of the element. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The quantification of analytes can be accomplished using external calibration, the internal standard (IS) method, or, if MS is used for detection, the isotope dilution method. They identified and analyzed the most important rye bread crumb aroma compounds quantitatively, using stable isotope dilution assays. Identification of likely PKU cases by the NeoGram Phenylalanine Test System is accomplished by isotope dilution MS/MS, whereby a sample extracted with a solution containing relevant internal standards from the kit is introduced into the tandem mass spectrometer (two mass filters linked by a central collision cell). |
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