isovaleric acid


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isovaleric acid

[¦ī·sō·və′ler·ik ′as·əd]
(organic chemistry)
(CH3)2CHCH2COOH Color-less liquid with disagreeable taste and aroma; boils at 176°C; soluble in alcohol and ether; found in valeriana, hop, tobacco, and other plants; used in flavors, perfumes, and medicines.
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73 which occurred during fermentation was most likely the result of increased acetic acid as the concentrations of propionic acid, isobutyric acid, butyric acid, isovaleric acid and valeric acid remained below 2.
The alfalfa hay/ grain diet produced significantly higher pH, acetic, propionic and isovaleric acid concentrations when compared to the bromegrass hay diet.
When leucine is not used properly, it builds up as isovaleric acid and other harmful substances in the blood and urine that are toxic or poisonous.
Due to the isovaleric acid released on the decomposition of the valepotriates, a distinctive pungent odor is produced (Mills 2000, Culpeper 1826).
For juniper, isovaleric acid was detected in the second replicate but not the first, while valeric acid was detected in the first but not the second.
During remission the goal of therapy is to prevent acute attacks of isovaleric acidemia by minimizing the accumulation of isovaleric acid and 3-hydroxyisovaleric acid, as well as to prevent the depletion of carnitine stores.
Prior studies by others had awarded that distinction to steroids and isovaleric acid.
D Aliyu and Nwabueze (2007) synthesis and solution studies of coppor (11) valeric and isovaleric acid hydrazide in aqueous, medium J.
On the base of pharmacological studies (19992009) for the standardization and quality control of herbal medicinal plants, we have developed recommendations concerning historical and traditional priority--technology of production of ecologically sound standards of raw materials and products of medicinal, aromatic, spicery and poisonous plants of our country : Foeniculum vulgate L--essential oils-3-5%, flvonoids -0,5%; Valeriana officinalis L--exstracted solids 27,8%, essential oils- 2%, isovaleric acid 0,91; Melissa officinalis L--essential oils 0,33%, vitamins C 150 mg%, carotene 7mg%; Carum carvi L--essential oils--7,2%; Thymus vulgaris L--essential oils 2,2%, Salvia officinalis L2,5%; Hyoscyamus niger L--alkaloids -0,5%;
Isovaleric acidemia (IVA) [4] (OMIM #243500) is caused by a defect in leucine catabolism due to deficiency of isovaleryl-coenzyme A (CoA) dehydrogenase, leading to the accumulation of free isovaleric acid, 3-hydroxyisovaleric acid, N-isovalerylglycine, and isovalerylcarnitine (C5).