Table 7 Antifilarial activity of Alnus nepalensis and DEC against Brugia malayi in jirds (Meriones unguicuIatus).
50] values, therefore followed up for in vivo testing in jird model harboring transplanted adult worms of B.
Host animals A B C Daurian ground squirrel 1 4962 4963 Siberian chipmunk 1 4965 4966 1 4964 4965 Tricolored squirrel 2 4977 1 4977 American red squirrel 1 4971 Southern flying squirrel 1 4972 4973 Columbian ground squirrel 1 4957 4958 Richardson's ground squirrel 2 4959 4960 1 4954 4959 1 4954 4955 Fat-tailed gerbil 3 Golden spiny mouse 1 Fat sand rat 1 Bushy-tailed jird
1 1 1 Large Egyptian gerbil 1 Greater Egyptian jerboa 1 4975 4976 1 Lesser Egyptian jerboa 1 GenBank accession nos.
(Meriones libycus), jird
carcasses, rodent burrows, and rodent excreta were found at the camel corral.
Although the organism is not known to cause overt disease in local cattle and did not infect jirds
injected with several-day-old blood from infected reindeer (30), the biologic data available to date are not definitive.
Attempts to obtain an isolate of the parasite that infected the Austrian patient, by injecting specimens of his blood into jirds
, were unsuccessful; the smears of blood from periodic tail snips and PCR analysis of blood obtained by cardiac puncture of the jirds
Although spirochetes readily pass between ticks confined in the same feeding chamber, none do so when the infected ticks feed on the back of a mouse while noninfected ticks are feeding on the mouse's head (3), when attached to different ears of a jird
(5), or when the distance separating the infected from the noninfected ticks is 3 cm (4).
(Meriones unguiculatus) and two that had fed on noninfected jirds