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Karyorrhexis

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karyorrhexis [‚kar·ē·ə′rek·səs]
(cell and molecular biology)
Fragmentation of a nucleus with scattering of the pieces in the cytoplasm.

Karyorrhexis 

the breakdown of a cell nucleus into parts; one of the intermediate stages of necrobiosis (after karyopyknosis and before karyolysis) that precedes the death of a cell. The nuclear membrane is destroyed and the nucleic acids show up asseparate clumps in the cytoplasm.



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This process is characterized by patchy, circumscribed or confluent areas of necrosis that are associated with karyorrhexis (figure 1).
This necrosis was characterized by lymphocytic karyorrhexis in the white pulp, and fibrinoid necrosis, congestion, and endothelial cell swelling in the red pulp, accompanied by cell debris.
A: When normal or benign cells die, they go through karyorrhexis, a process in which you see fragmentation of nuclei.
 
 
 
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