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khellin

   Also found in: Wikipedia 0.01 sec.
khellin [′kel·ən]
(pharmacology)
C14H12O5A synthetic compound that crystallizes from methanol solution, has a bitter taste, melts at 154-155°C, and is more soluble in water than in organic solvents; used in medicine as an antispasmodic, a coronary vasodilator, and a bronchodilator. Also spelled chellin; khelin. Also known as visammin.


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Conventional antiasthmatic compounds, such as sodium cromolyn and sodium cromoglycate, were developed from analogs of the naturally occurring furanochromone khellin (visammin), found in the Asian plant Ammi visnaga.
Bashar Mohammad Harb Hamad In recognition of a programme of work entitled, "Synthesis and Pharmacological Evaluation of Novel Khellin Analogues as Potential Cardioprotective Agents", carried out at Coventry University, under the direction and supervision of Dr T Javed, Senior Lecturer, School of Science and the Environment, Coventry University and Dr S O Fagbemi, Senior Lecturer, Department of Forensic and Biomedical Sciences, Faculty of Health Life and Social Sciences, University of Lincoln.
 
 
 
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