kilobase


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kilobase

[′kil·ō‚bās]
(genetics)
Unit of length equal to 1000 base pairs in deoxyribonucleic acid or 1000 nitrogenous bases in ribonucleic acid. Abbreviated kb; kbp.
References in periodicals archive ?
These genes were differentially expressed by at least 2-fold and had more than five reads per kilobase of exon gene model (RPKM) in at least one sample.
These results provide direct evidence that asbestos fibers induced kilobase pair deletion mutations in a transgenic mouse mutation system, and that these were mediated by oxyradicals.
3 kilobase (kb) section, specific, reciprocal translocations are common.
Fragments per kilobase of exon per million fragments (FPKM) of each sample were calculated to estimate the expression levels of the genes.
Uniparental inheritance of microsatellite alleles of the cystic fibrosis gene (CFTR): identification of a 50 kilobase deletion.
Simulation experiments indicate that a copy number increase of 50% should be detectable if the region is 2 megabase pairs (Mbp) or larger, and an amplified region (amplicon) of 250 kilobase pairs (kbp) would need a 400% copy number increase to be detectable with metaphase CGH.
Restriction fragments were visualized by autoradiography and their sizes estimated by comparison to a 1 kilobase size ladder (New England Biolabs).
A Bethesda Research Laboratories 1 kilobase pair (kbp) ladder was run in each gel as a molecular weight size standard.
Fractions between 100 and 300 kilobase pairs (kbp) were cut from the gel and inserted into a second gel and run at a constant 3- to 5-s switch time to remove small trapped DNA fragments.