kinase


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Related to kinase: mutase, creatine kinase, Thymidine kinase

kinase

[′kī‚nās]
(biochemistry)
Any enzyme that catalyzes phosphorylation reactions.
References in periodicals archive ?
The market currently has seven approved non-tyrosine kinase inhibitors.
There are total seven marketed non-tyrosine kinase inhibitors approved so far.
CaM kinase adds phosphate groups to other proteins, a process known as phosphorylation.
p38 MAP kinase pathway regulates angiotensin II-induced contraction of rat vascular smooth muscle.
We feel that the PLK1-B23 phosphorylation story nicely demonstrates the power of the Kinetworks(TM) approach to rapidly and cost-effectively discover protein kinase drug targets and the means to identify their inhibitors" said Dr.
A novel putative tyrosine kinase receptor encoded by the eph gene.
Exposure to R5 gp120 and X4 gp 120 resulted in activation of pro line-rich tyrosine kinase 2 (Pyk2), a non-receptor tyrosine kinase related to focal adhesion kinase.
In CML cells, Bcr-Abl tyrosine kinase adds phosphate groups to a protein called Crkl.
KINOMEscan, now part of DiscoveRx, is a leading provider of kinase inhibitor profiling services to the kinase drug discovery industry.
Tyrosine kinase therapeutics segment is rapidly growing along with numerous products at various phases of industry life cycle.
The discovery and development of targeted kinase inhibitors has often utilized a structure-based approach to the design of small molecule drugs that bind specifically within the ATP binding site of a target kinase.
Members of the phosphatidylinositol 3-kinase--related kinase (PIKK) family such as DNA-activated protein kinase (DNA-PK) and ataxia-telangiectasia mutated (ATM) have been implicated in the phosphorylation of p53 at Ser15 (Giaccia and Kastan 1998; Lakin and Jackson 1999; Meek 1998).