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centromere |
Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson | 0.20 sec. |
centromereStructure in a chromosome that holds together the two chromatids. It is the point of attachment to the structure that pulls the chromatids to opposite ends of the cell during cell division (see mitosis). During the middle stage of mitosis, the centromere duplicates and the chromatid pair separates, each chromatid becoming a separate chromosome. Thus, when the cell divides, both daughter cells have complete sets of chromosomes. |
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Chromosomal localization of the genes encoding the kinetochore proteins CENPE and CENPF to human chromosomes 4q24 [right arrow] q25 and 1q32 [right arrow] q41, respectively, by fluorescence in situ hybridization. Kinetochores and centrosomes play crucial roles in distributing identical sets of chromosomes within a dividing cell, says Potter. Kinetochore detection in micronuclei: an alternative method for measuring chromosome loss. |
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