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lymphocyte
(redirected from large lymphocyte)

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lymphocyte: see blood blood, fluid pumped by the heart that circulates throughout the body via the arteries, veins, and capillaries (see circulatory system; heart). An adult male of average size normally has about 6 quarts (5.6 liters) of blood.
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; immunity immunity, ability of an organism to resist disease by identifying and destroying foreign substances or organisms. Although all animals have some immune capabilities, little is known about nonmammalian immunity.
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lymphocyte

Enlarge picture
Human lymphocyte (phase-contrast microphotograph).
(credit: Manfred Kage—Peter Arnold)
Type of leukocyte fundamental to the immune system, regulating and participating in acquired immunity. Each has receptor molecules on its surface that bind to a specific antigen. The two primary types, B cells and T cells, originate from stem cells in bone marrow and travel to lymphoid tissues. When a B cell binds to an antigen, it multiplies to form a clone of identical cells. Some of these, acted on by helper T cells, differentiate into plasma cells that produce antibodies against the antigen. Others (memory cells) multiply, providing long-term immunity to the antigen.


lymphocyte
a type of white blood cell formed in lymphoid tissue

lymphocyte [′lim·fə‚sīt]
(histology)
An agranular leukocyte formed primarily in lymphoid tissue; occurs as the principal cell type of lymph and composes 20-30% of the blood leukocytes.


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In patients with human immunodeficiency virus, a high BMG level in the absence of renal failure indicates a large lymphocyte turnover rate, which suggests the virus is killing lymphocytes.
After evaluation of a gate that encompassed at least 95% of all lymphocytes, selective gates that encompassed small, intermediate, and large lymphocytes were evaluated.
If LUC[greater than]4%, review smear: if reactive lymphocytes, append LUCs with "atypical lymphs" comment; if large lymphocytes or agranular monocytes, add back to lymph or mono % and absolute counts, respectively; if abnormal cells, do manual differential.
 
 
 
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