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| Results presented at DDW showed that nearly half of constipated patients with advanced illness experienced laxation (bowel movement) within four hours of receiving their first dose of methylnaltrexone (0. In this second phase 3 clinical study, subcutaneous administration of MNTX induced laxation (bowel movement) within four hours in 51. The primary efficacy endpoint, laxation within four hours, was highly statistically significant at both MNTX doses tested. |
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