If animals are missing leptin
, or the leptin
receptor, they eat too much and become much too obese.
But the brain's leptin
machinery is a problematic target, says neuroscientist Jenni Harvey of the University of Dundee in Scotland.
2]) play an important role in determining the plasma concentration of leptin
in mammals (Cella et al.
duzeyleri enzyme linked immunosorbent assay (ELISA) yontemi ile olculdu.
Ikisi de numerik olan leptin
seviyeleri ile 24 saatlik tansiyon Holter ve ritim Holter parametrelerinin karsilastirmasinda korelasyon testi kullanildi.
The results showed that after swimming chronic stress, plasma leptin
concentration was significantly increased.
Unal et al measured leptin
concentrations in trained young male athletes (from different sports) and in healthy sedentary subjects.
expression is associated with chemoresistance, but at the same time is also a favorable therapy-independent biomarker, so this combination of predictive and therapy-independent prognostic impacts mean that leptin
has the potential to be a clinically useful biomarker.
A human clinical trial currently underway aims to determine whether adding leptin
to standard insulin therapy might help rein in the tumultuous blood-sugar levels of people with type 1 diabetes.
It has been reported that short-term training sessions (<12 weeks) do not have an impact on leptin
levels so long as they do not reduce fat mass, while long-term training sessions (>12 weeks) decrease leptin
levels (Kraemer and Castracane, 2007).
At the time that the discovery of leptin
was reported, I was working in Dr.
This review traces how energy metabolism affects osteoblasts through the central control of bone mass involving leptin
, serotoninergic neurons, the hypothalamus, and the sympathetic nervous system.