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lethal dose 50

   Also found in: Medical, Acronyms, Wikipedia 0.03 sec.
lethal dose 50 [′lē·thəl ¦dōs ′fif·tē]
(pharmacology)
The dose of a substance which is fatal to 50% of the test animals. Abbreviated LD50. Also known as median lethal dose.


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While acknowledging that some animal tests, such as the Lethal Dose 50 Percent (LD50) and the Maximum Tolerated Dose (MTD), may yield results that are statistically invalid and difficult to extrapolate to humans, he nevertheless concludes, "Though imperfect, in most tests the mouse ramains the best model for man.
 
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