lethal gene


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Related to lethal gene: epistasis

lethal gene

[′lē·thəl ′jēn]
(genetics)
A gene mutation that causes premature death in heterozygotes if dominant, and in homozygotes if recessive. Also known as lethal mutation.
References in periodicals archive ?
The breed became virtually extinct after developing a lethal gene that rendered a large proportion of their eggs infertile.
In one fruit fly line, the team inserted a three-part genetic time bomb: a lethal gene that disrupts signaling in cells, a switch controlling it that flips only in females, and a control for that switch that keeps it in its off state when the fly consumes the antibiotic tetracycline.
It has long been known that Queen Victoria was a carrier of the lethal gene of haemophilia, but we are presented here with the results of the first extended scientific examination of the history of haemophilia in the royal families of Europe.
Martin knew she had the same potentially lethal gene that prompted her famous niece to have the operation on her breasts.