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levodopa

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia, Hutchinson 0.07 sec.
levodopa: see l-dopa l-dopa (ĕl-dō`pə)
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levodopa

 or L-dopa

Organic compound (L-3,4-dihydroxyphenylalanine) from which the body makes dopamine, a neurotransmitter deficient in persons with parkinsonism. When given orally in large daily doses, levodopa can lessen the effects of the disease. However, it becomes less effective over time and causes abnormal involuntary movements (dyskinesia).


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Analysis will span the de novo stage, early in the disease process before levodopa or other PD medications have commenced, through to end-stage disease, which is often 20 to 30 years later.
Imaging can also reveal the effect of Parkinson's therapies such as levodopa, which replaces depleted dopamine, and deep-brain stimulation, in which doctors install in the brain a pacemakerlike device that sends electric pulses to target areas to prevent the signals that cause tremors and rigidity (SN: 3/12/05,p.
In a randomized controlled trial, we investigated the effects of a single dose of levodopa on T-reflex amplitude in sexually aroused men and women.
 
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