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lichenification

   Also found in: Medical, Wikipedia 0.01 sec.
lichenification [lī‚ken·ə·fə′kā·shən]
(medicine)
The process whereby the skin becomes leathery and hardened; often the result of chronic pruritis and the irritation produced by scratching or rubbing eruptions.


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The primary endpoint was a summary score for erythema, edema/papulation, oozing/crust, excoriation and lichenification according to a 4-point scale.
Generic term for inflammatory conditions of the skin, particularly with vesiculation in the acute stage, typically erythematous, edematous, papular, and crusting; followed often by lichenification and scaling and occasionally by duskiness of the erythema and, infrequently, hyperpigmentation; often accompanied by sensations of itching and burning; the vesicles form by intraepidermal spongiosis; often hereditary and associated with allergic rhinitis and asthma.
When facial skin thickens, the visibility of the skin''s normal markings increases; this is called lichenification.
 
 
 
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