ligation

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ligation

[lī′gā·shən]
(medicine)
Surgical tying of vessels or ducts with a ligature.
(cell and molecular biology)
The process of joining two adjacent nitrogenous bases separated by a nick in one strand of a deoxyribonucleic acid duplex or of two linear nucleic acid molecules.
Formation of a phosphodiester bond to join adjacent nucleotides in the same nucleic acid chain.