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linkage group |
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linkage groupAll the genes on a single chromosome. They are inherited as a group; during cell division they act and move as a unit rather than independently. Variations in linkage groups can occur if a chromosome breaks, and the sections join with the partner chromosome if it has broken in the same places. This exchange of genes between chromosomes, called crossing-over, usually occurs during meiosis. Sex linkage is the tendency of a characteristic to be linked to one sex; sex-linked traits in humans include red-green colour blindness and hemophilia. |
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Among model organisms, genetic mapping is most well established in the mouse, having begun in 1915 with the discovery of the first linkage group (16). |
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