lipid storage disease

lipid storage disease

Any of a group of relatively rare hereditary disorders of fat metabolism in which enzyme defects cause distinctive types of lipids to accumulate. They include Tay-Sachs disease, Gaucher disease, Niemann-Pick disease, and Fabry disease. Several are untreatable and cause death before age five; others occur in adulthood.

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lipid storage disease [′lip·əd ‚stȯr·ij di‚zēz]

(medicine)

Any of various rare diseases characterized by the accumulation of large histiocytes containing lipids throughout reticuloendothelial tissues; examples are Goucher's disease, Niemann-Pick disease, and amaurotic familial idiocy.