When this protein crosses the blood-brain barrier, it provides the brain with information about the body's fat deposits, and thus acts as a part of the feedback mechanism that can function as a lipostat
Some suggested that leptin influenced the hedonic perception of food, and that, as a lipostat
, it was part of a natural system that attempts to maintain total body adiposity within a stable range.
The traditional idea of a 'set point' (Mrosovsky and Powley, 1977) by which energy balance is monitored through some negative feedback loop to correct feeding behaviour, has been recently advanced by the discovery of leptin and the development of the lipostat
Noon worked at Bristol Myers Squibb, first as marketing director responsible for the product launch of the drug Lipostat
, and later was promoted to general manager, U.
Lipitor, a type of statin, was found not only to clear plaque and fight hardening of the arteries, but was also better at cutting production of bad cholesterol when compared with another statin, lipostat