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vaccine |
Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson | 0.04 sec. |
vaccinePreparation containing either killed or weakened live microorganisms or their toxins, introduced by mouth, by injection, or by nasal spray to stimulate production of antibodies against an infectious agent. This confers immunity to that agent, since the B lymphocytes remain sensitized to it and respond to later infection by producing more antibodies. The first vaccine, against smallpox, was introduced by Edward Jenner in 1798. Vaccines have been developed against diseases caused by bacteria (e.g., typhoid, whooping cough, tuberculosis) and by viruses (e.g., measles, influenza, rabies, poliomyelitis). Effectiveness varies, and a small percentage of people have adverse reactions. Those with immunodeficiency disorders should not receive live vaccines. vaccine Med 1. a suspension of dead, attenuated, or otherwise modified microorganisms (viruses, bacteria, or rickettsiae) for inoculation to produce immunity to a disease by stimulating the production of antibodies 2. (originally) a preparation of the virus of cowpox taken from infected cows and inoculated in humans to produce immunity to smallpox 3. of or relating to vaccination or vaccinia 4. Computing a piece of software designed to detect and remove computer viruses from a system vaccine [vak′sēn] (immunology) A suspension of killed or attenuated bacteria or viruses or fractions thereof, injected to produce active immunity. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Interest in a potential attenuated live vaccine has been stimulated by the finding that targeted disruption of the Blastomyces dermatitidis gene, which encodes the surface adhesin BAD-l, renders the mutant avirulent. The MMR vaccine, added to the vaccine schedule in 1979, is a live vaccine and does not contain a preservative. Of the 9,000 doses of live vaccine shipped to the Los Angeles County Health Department, fewer than 100 public health workers have volunteered to be immunized - and just 10 employees at Santa Clarita's only hospital. |
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