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loss of heterozygosity |
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loss of heterozygosity [¦lȯs əv ‚hed·e·rō·zī′gäs·əd·ē]
(genetics) In a heterozygote, the loss of one of the two alleles at one or more loci in a cell lineage or cancer cell population due to chromosome loss, deletion, or mitotic crossing-over. Abbreviated LOH. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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