freeze drying

(redirected from lyophilizer)
Also found in: Dictionary, Thesaurus, Medical, Wikipedia.

freeze drying

[′frēz ‚drī·iŋ]
(engineering)
A method of drying materials, such as certain foods, that would be destroyed by the loss of volatile ingredients or by drying temperatures above the freezing point; the material is frozen under high vacuum so that ice or other frozen solvent will quickly sublime and a porous solid remain.
References in periodicals archive ?
TABLE 10 SHELF SIZE AND AREA OF DRYING SHELVES IN A TYPICAL LYOPHILIZER 42
The facility boasts 10 lyophilizers ranging in capacities from 4 sq.
Currently, control systems follow the architecture of PLC system for actuation of the mechanical components of the lyophilizer or loading systems, which connects to a PC or HMI," he says.
The production facility utilizes three high-speed filling lines, four lyophilizers and a clinical fill line.
During fourth-quarter 2004 significant progress was made toward completing the validation process for the Company's second lyophilizer unit, which should triple existing lyophilization capacity over time.
We have to create the proper environment where vials can be filled and sent to the lyophilizer and then back out again and crimped in an aseptic environment.
Inside Sterile University OsoBio has set up fully functioning equipment such as a filler and a lyophilizer to enable new employees to get hands-on experience working with the equipment before they go into the sterile "core" of the manufacturing areas.
On July 28, 2003, Draxis received insurance proceeds of $700 in settlement of physical damage and business interruption losses related to installation problems of its first lyophilizer unit in 2000.
DRAXIS Pharma commenced commercial production of freeze-dried sterile products during the second quarter 2005 upon the final validation of the recently installed second lyophilizer unit.
The specialized facility was originally designed to readily accommodate this second lyophilizer at a cost significantly less than that of the initial installation with minimal disruption to ongoing production.
The lyophilization line and the specialized facility in which it is housed have been designed to readily accommodate a second lyophilizer, which will allow DRAXIS to double production capacity at a cost significantly lower than that of the initial installation.