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macrocyclic compound

   Also found in: Wikipedia 0.01 sec.
macrocyclic compound [¦mak·rō‚sī ′käm‚pau̇nd]
(organic chemistry)
An organic compound containing a large ring, that is, a closed chain of 12 or more carbon atoms; examples include crown ethers, cryptands, spherands, carcerands, cyclodextrins, cyclophanes, and calixarenes. Also known as macrocycle.
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Tranzyme is also pursuing development of several other macrocyclic compounds emanating from its internal research program, including a second generation, oral ghrelin agonist, TZP-102, currently in Phase 2 trials, and two preclinical compounds, TZP-201 for severe diarrhea indications such as chemotherapy-induced diarrhea, and TZP-301, a ghrelin antagonist, for metabolic disorders.
Tranzyme Pharma to Present at American Chemical Society (ACS) 2009 ... by Business Wire
Patent and Trademark Office (USPTO) for two patent applications entitled "Macrocyclic Modulators of the Ghrelin Receptor" and "Spatially-Defined Macrocyclic Compounds Useful for Drug Discovery".
Tranzyme Pharma Receives Notices of Allowance from USPTO on Two ... by Business Wire
amp; SHERBROOKE, Quebec -- Tranzyme Pharma, a leading biopharmaceutical company developing novel mechanism-based therapeutics for the treatment of gastrointestinal (GI) and metabolic disorders, announced today the issuance of a European patent (EP 1 218 403) entitled "Combinatorial Synthesis of Libraries of Macrocyclic Compounds Useful in Drug Discovery.
Tranzyme Pharma Announces Issuance of European Patent Protecting ... by Business Wire
 
 
 
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