macroencapsulation

macroencapsulation

[‚mak·rō·in‚kap·sə′lā·shən]
(cell and molecular biology)
The envelopment of a large mass of xenotransplanted cells or tissue in planar membranes, hollow fibers, or diffusion chambers to isolate the cells from the body, thereby avoiding the immune responses that the foreign cells could initiate, and also to allow the desired metabolites (such as insulin and glucose for pancreatic islet cells) to diffuse in and out of the membrane.
References in periodicals archive ?
The article, entitled "Insulin-Producing Endocrine Cells Differentiated In Vitro From Human Embryonic Stem Cells Function in Macroencapsulation Devices In Vivo," is published in Stem Cells Translational Medicine(October 2015 issue; e-published online August 24, 2015).
Food Encapsulation Market by Technology (Microencapsulation, Macroencapsulation, Nanoencapsulation, Hybrid) by Shell Materials (Hydrocolloids, Lipids, Polymers, Melts) by Core Phase (Vitamins, Minerals, Probiotics, Colors, Flavors & Essence) - Global Trends & Forecasts to 2018
Although hollow-fibre membranes also have their size limits (11), the impetus for larger devices has nonetheless driven the development of polymers especially suitable for macroencapsulation.
According to the bill, those methods include cell fusion, microencapsulation and macroencapsulation, and recombinant DNA technology.
WCS plans to promptly begin tests using EKOR on certain wastes that can use macroencapsulation technology to comply with RCRA, TSCA, and/or radiological criteria.
TABLE 11 GLOBAL MACROENCAPSULATION MARKET BY GEOGRAPHY 2007 - 2014 ($MILLIONS)
The VC-01 combination product candidate, comprised of human pancreatic progenitor cells in a macroencapsulation device, is intended to address both of the main limitations of islet transplantation.
The market research report " Food Encapsulation Market by Technology (Microencapsulation, Macroencapsulation, Nanoencapsulation, Hybrid) , by Shell Materials (Hydrocolloids, Lipids, Polymers, Melts) , by Core Phase (Vitamins, Minerals, Probiotics, Colors, Flavors & Essence) - Global Trends & Forecasts to 2018", defines and segments the food encapsulation market with an analysis and forecast of values.
ViaCyte's VC-01(TM) product candidate, being assessed in the STEP ONE clinical trial, employs pluripotent stem cell-derived PEC-01(TM) pancreatic progenitor cells implanted within the Encaptra macroencapsulation device.
The VC-01 combination product employs a macroencapsulation device that is designed to protect the implanted cells from the patient's immune system.
JDRF is partnering with Beta-O2 in order to speed up the testing of EAir, an implantable macroencapsulation system composed of an immune protection unit (about two and a half inches across) connected to ports through which oxygen can be periodically injected to support the survival of the enclosed beta cells or islets.
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