macroencapsulation

macroencapsulation

[‚mak·rō·in‚kap·sə′lā·shən]
(cell and molecular biology)
The envelopment of a large mass of xenotransplanted cells or tissue in planar membranes, hollow fibers, or diffusion chambers to isolate the cells from the body, thereby avoiding the immune responses that the foreign cells could initiate, and also to allow the desired metabolites (such as insulin and glucose for pancreatic islet cells) to diffuse in and out of the membrane.
References in periodicals archive ?
Lim, Macroencapsulation of Quorum Quenching Bacteria by Polymeric Membrane Layer and its Application to MBR for Biofouling Control, J.
Citation: "Insulin-Producing Endocrine Cells Differentiated In Vitro From Human Embryonic Stem Cells Function in Macroencapsulation Devices In Vivo," Alan D.
The VC-01 combination product employs a macroencapsulation device that is designed to protect the implanted cells from the patient's immune system.
Although hollow-fibre membranes also have their size limits (11), the impetus for larger devices has nonetheless driven the development of polymers especially suitable for macroencapsulation.
With the immunoisolation characteristics of hollow-fibre membranes still in question, a discussion of other polymer membranes suitable for macroencapsulation is timely.
According to the bill, those methods include cell fusion, microencapsulation and macroencapsulation, and recombinant DNA technology.
WCS plans to promptly begin tests using EKOR on certain wastes that can use macroencapsulation technology to comply with RCRA, TSCA, and/or radiological criteria.
Previously, Envirocare commercialized another BNL-developed mixed-waste process called macroencapsulation.
TABLE 11 GLOBAL MACROENCAPSULATION MARKET BY GEOGRAPHY 2007 - 2014 ($MILLIONS)
This support has directly aided the development of VC-01, a regenerative medicine, combination product consisting of pancreatic beta cell progenitors encapsulated in a durable macroencapsulation device.
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