11) One school of thought is that syndromic management of non-gonococcal urethritis using macrolide antibiotic
treatments causes strains containing macrolide mutations to predominate, resulting in dmg resistance.
40) The authors found that a reduction of macrolide antibiotic
consumption in Finland led to a reduction in streptococci macrolide resistance from 16.
Summary: Clarithromycin is a macrolide antibiotic
effective against bacteria by interfering their protein synthesis.
Erythromycin is a macrolide antibiotic
produced by Saccharopolyspora erythraea.
The investigators showed further that the macrolide antibiotic
clarithromycin, a negative allosteric modulator of GABA-A receptors, reduced sleepiness in patients with central hypersomnolence syndromes in a randomized, double-blind, crossover trial (Ann Neurol.
At Cempra we have taken a macrolide antibiotic
from lead selection to the NDA I have had a history of antibiotic development and have worked in Pharma since 1980.
Taken together, the researchers say the more pronounced effects of tylosin on weight gain and microbiome disruption are especially worrisome, given the increasing popularity of macrolide antibiotic
prescriptions for children.
Suppressive activity of a macrolide antibiotic
, roxithromycin, on pro-inflammatory cytokine production in vitro and in vivo.
Madam, Azithromycin is a broad spectrum macrolide antibiotic
that is widely used to treat bacterial infections.
The complete structure of the polyene macrolide antibiotic
Presently, the fourth generation macrolide antibiotic
is in Phase 3 development for community-acquired bacterial pneumonia in adults.
Coadministering a cytochrome P450 isoenzyme 3A4 (CYP3A4)inhibiting macrolide antibiotic
, such as clarithromycin or erythromycin) (but not azithromycin) with atorvastatin (Lipitor[R]), simvastatin (Zocor[R]), or lovastatin (Mevacor[R]), which are metabolized by CYP3 A4, is associated with a fourfold to 10-fold increase in statin concentrations.