1,2) It is characterized by a central maculopapule
with a peripheral ring of scales, specifically notable on the palms and soles.
The former caused different kinds of eruptions such as maculopapule
, excoriation, blisters, edema, ulcer, and the latter caused jaundice, hepatosplenomegaly or abnormal hepatic function.
4 Numerous reddish-brown or pale, monomorphic maculopapules
, plaques or nodules appear in a symmetrical distribution in various locations on the body (except the face, head, palms, and soles) with the highest concentration usually being on the trunk and thighs.
A patient with UP may present with brown or reddish maculopapules
, papules, nodules, pruritus, and flushing of the face.
The BRAF inhibitors are associated with a nonspecific rash consisting of maculopapules
and features similar to those of keratosis pilaris, giving the skin a sandpaperlike appearance.
Nonpruritic rashes developed in all patients and involved predominantly the trunk and extremities, represented by maculopapules
on 8 patients, papulovesicles on 5 patients, and petechiae on 2 patients (Figure 2, panels B, C).
Cutaneous manifestations of CSS are present in approximately 50% of patients and may be divided into three categories: erythematous maculopapules
, hemorrhagic lesions and cutaneous or subcutaneous nodules.
2 Specific lesions include papules maculopapules
plaques nodules lupus pernio scar sarcoid ulcerative lesions hypopigmentation and many others.