major gene


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major gene

[′mā·jər ‚jēn]
(genetics)
Any gene individually associated with pronounced phenotypic effects.
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References in periodicals archive ?
Evidence for a major gene elevating serum bilirubin concentration in Utah pedigrees.
Thus, the G1 mutation locus of GDF9 is not the major gene contributing to the large lambing number per lambing.
2009) also found that genotype distributions of BM P15 gene were significantly different among those goat breeds and preliminarily indicated that the BM P15 gene is either a major gene which affects the prolificacy in Jining Grey goats or a molecular marker in close linkage with such a gene.
Major Gene Maxwell, A Company Royal Scots, said: ``The boys will appreciate most things.
A recent family heart study inferred the existence of a major gene for high bilirubin concentrations that may protect against CHD (9).
The generosity of VNG will touch area families by heating their homes and warming their hearts," said Major Gene A.
Before applying MAS, or starting to search for quantitative trait loci (QTL), identification of a major gene based on statistical segregation analyses using only phenotypic data would be informative, cheap and useful, as compared to MAS.
As the first major gene identified to cause gout, we believe that ABCG2 also represents an attractive new drug target," says Dr.
For example, many segregation studies have been done and failed to detect major gene loci influencing variation of HDL-C in either Caucasian or non-Caucasian populations (12-14).
More than 30 major gene companies were launched in the past eight years and several thousand people have received gene therapy.
Segregation analysis in a population from Desirade Island (French West Indies) has demonstrated that susceptibility to leprosy (regardless of the clinically defined subtype) is controlled by a major gene not linked to the major histocompatibility complex (52).