major histocompatibility complex


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Related to major histocompatibility complex: human leukocyte antigen

major histocompatibility complex

[′mā·jər ¦hi·stō·kəm′pad·ə′bil·əd·ē ′käm‚pleks]
(immunology)
In vertebrates, a family of genes that encode cell surface glycoproteins that regulate interactions among cells of the immune system, some components of the complement system, and perhaps other related functions connected with intercell recognition. Abbreviated MHC.
References in periodicals archive ?
Influence of the major histocompatibility complex on tumor regression and immunity in chickens.
Rat intestinal M cells contain acidic endosomal-lysosomal compartments and express class II major histocompatibility complex determinants.
today announced the commercial availability of the HLASeq[TM] Research Screening Panel, a comprehensive genetic screening solution for human leukocyte antigen (HLA) and major histocompatibility complex (MHC) research using next-generation sequencing technology.
Bovine leukocyte antigen major histocompatibility complex class II DRB3 * 2703 and DRB * 1501 alleles are associated with variation in levels of protection against Theileria parva challenge following immunization with sporozoite p67 antigen.
The San Nicolas Island foxes (Urocyon littoralis dickeyi) vary considerably in the genes coding for immune system compounds known collectively as the major histocompatibility complex (MHC), report Andres Aguilar of the University of California, Santa Cruz and his colleagues.
They also enhance the actions of the anti-inflammatory cytokines transforming growth factor-beta and intefieukin-10 and induce upregulation of major histocompatibility complex class II molecules (Curr.
Segregation analysis with a combination of Salmonella-resistant and Salmonella-susceptible lines has shown that resistance to infection is fully dominant and is not sex-linked or associated with the major histocompatibility complex (47).
The composition of matter patent (United States Patent 5,734,023) affords fundamental protection for the company's unique approach to the binding of key disease-specific proteins or peptides to a subunit of the disease-associated major histocompatibility complex (MHC's class II).
In the study, they used ultra-deep sequencing with the Genome Sequencer FLX System from 454 Life Sciences, a Roche Company (SWX:RO) (SWX:ROG) (Pink Sheets: RHHBY), to perform rapid major histocompatibility complex (MHC) class I genotyping in macaques, a common model primate.
Washington, June 25 (ANI): Scientists have found four new genetic variants in the major histocompatibility complex (MHC) that confer a higher risk of systemic lupus erythemathosus (lupus) in African- American women.
Cytomegalovirus prevents antigen presentation by blocking the transport of peptide-loaded major histocompatibility complex class I molecules into the medial-Golgi compartment.

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