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malaria pigment

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malaria pigment [mə′ler·ē·ə ‚pig·mənt]
(pathology)
Dark-brown, amorphous, microcrystalline and birefringent pigment found in parasitized erythrocytes, especially with malarial parasites, and in littoral phagocytes of spleen, liver, and bone marrow.


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2 mmol/l) Acidosis (plasma bicarbonate <15 mmol/l or serum lactate >5 mmol/l) Hepatic transaminases >3 times normal Renal impairment (serum creatinine >265 [micro]mol/l or rapidly rising creatinine or urine output <400 ml/day in an adult) Haemoglobin <5 g/l Parasitaemia [greater than or equal to] 5% [greater than or equal to] 5% neutrophils contain malaria pigment Presence of schizonts of P.
Sometimes parasites cannot be found in peripheral blood smear from patients with malaria, but malaria pigment may be seen in circulating phagocytic leucocytes.
Monocytes and neutrophils may ingest birefringent depolarizing malaria pigment that can be detected by the instrument.
 
 
 
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