malic enzyme


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malic enzyme

[′mal·ik ′en‚zīm]
(biochemistry)
An enzyme which utilizes nicotinamide-adenine dinucleotide phosphate (NADP) to catalyze the oxidative decarboxylation of malic acid to pyruvic acid and carbon dioxide. Also known as malate dehydrogenase.
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The team overexpressed an additional bacterialgene in this strain to produce malic enzyme.
Ten enzyme systems in starch gel were analyzed: Aspartate amino Transferase (AAT), Alcohol Dehydrogenase (ADH), Glucose-3-phosphate dehydrogenase (G3PD), Glucose-6-phosphate dehydrogenase (G6PD), Glucose phosphate Isomerase (GPI), Isocitrate Dehydrogenase (IDH), Lactate dehydrogenase (LDH), Malate dehydrogenase (MDH) Malic Enzyme (ME), Phosphoglucomutase (PGM), and Esterase (EST) in the polyacrylamide gel.
Cell-specific regulation of transcription of the malic enzyme gene: characterization of cisacting elements that modulate nuclear T3 receptor activity.
Saccharomyces cerevisiae-derived peptides reduce the activity of enzymes critical to the manufacture of fat from excess energy in foods, particularly glucose-6-phosphate dehydrogenase (G6PD) and malic enzyme (ME).
Genes relevantes sobre expresados en IB GEN ENTREZ GENE NAME FOLD CHANGE CASP 7 Caspase 7 2,02 ME1 Malic Enzyme 2,00 UBE2D4 Ubiquitin conjugating 1,57 enzyme ELOVL6 Fatty Acid Elongase 6 1,56 CASP4 Caspase 4 1,56 CTSL2 Cathepsin L2 1,44 Genes relevantes sobre expresados en DU x IB IGF2 Insuline-like ggrowth factor 2 -4,87 COL12A1 Collagen type XII alpha 1 -2,61 COL1A1 Collagen type I alpha 1 -2,17 UBA5 Ubiquitin-like modifier act.
It has been demonstrated that the cytosolic NAD (P)- dependent dehydrogenases6 and NADP malic enzyme are inhibited by MTX, indicating that the drug could decrease the availability of NADPH in cells by inhibiting pentose cycle enzymes.
Using this method, activities of enzymes: glucose-6-phosphate dehydrogenase (G6PDG, malic enzyme (NADPMDG), NAD- and NADH-dependent lactate dehydrogenase (LDG and NADH-LDG), NAD- and NADH-dependent malate dehydrogenase (MDG and NADH-MDG), NADP- and NADPH-dependent glutamate dehydrogenase (NADP-GDG and NADPHGDG), NAD- and NADH-dependent glutamate dehydrogenase (NAD-GDG and NADH-GDG), NAD and NAD-dependent isocitrate dehydrogenase (NADICDG and NADP-ICDG), and glutathione reductase (GR) were studied.
Four enzymes were used for analysis of isolates: malate dehydrogenase (MDH), malic enzyme (ME), glucose phosphate isomerase (GPI), superoxide dismutase (SOD) (17,18).
Based on the results of our study, essential erythroid proteins (ankyrin recurrent and FYVE bundle containing protein 1, spectrin alpha, actin-depolymerization factor, actin-depolymerizing factor, LIM bundle and actin binding subunit 1 isoform a, LIM bundle and actin binding subunit 1 isoform b, NADP-dependent malic enzyme, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, mitochondrial NADP (+) dependent malic enzyme 3, ribulose bisphosphate-carboxylase large chain, maturase K) and the required ATP bioenergy (ATP synthase, ATP synthase beta subunit, ATP synthase alpha subunit, ATP-binding protein C12, TP synthase H+ transporter protein, ADF, and alpha-1,2-glycosyltransferase ALG10-A) are included in the protein library of Ankaferd.