malignant


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Related to malignant: malignant hyperthermia, malignant hypertension, malignant neoplasm, malignant melanoma, malignant tumor, Malignant narcissism

malignant

1. Pathol (of a tumour) uncontrollable or resistant to therapy; rapidly spreading
2. History (in the English Civil War) a Parliamentarian term for a royalist

malignant

[mə′līg·nənt]
(cell and molecular biology)
Pertaining to cells that have undergone phenotypic transformation by oncogenes or protooncogenes.
(medicine)
Endangering the life or health of an individual.
Of or pertaining to the growth and proliferation of certain neoplasms which terminate in death if not checked by treatment.
References in periodicals archive ?
In February 2000, the FDA approved ACTIMMUNE(R) for delaying the time to disease progression in patients with severe, malignant osteopetrosis.
Plexiform neurofibroma with and without associated malignant peripheral nerve sheath tumor: a clinicopathologic and immunohistochemical analysis of 54 cases.
Repeat open biopsy of the left parotid gland and inclusive lymph nodes later demonstrated benign parotid parenchyma with no evidence of malignant processes.
A review of the Malignant Pleural Mesothelioma products under development by companies and universities/research institutes based on information derived from company and industry-specific sources.
When the team injected the altered poliovirus into large malignant gliomas in mice, the tumors disappeared within days or weeks.
Non-Hodgkin lymphoma (NHL) belongs to the types of malignant diseases that have shown the largest increasing incidence in Sweden and in other Western countries during the second half of the 20th century.
Histologic examination revealed infiltration of the subepithelium by malignant melanocytes containing cytoplasmic and nuclear brown pigment (Figure 3).
TORONTO, April 15 /PRNewswire/ -- Updated results of a multi-center Phase II clinical trial testing the effect of IMUTEC Corporation's VIRULIZIN(TM) in patients with advanced malignant melanoma demonstrated, at the time of reporting, a one-year survival rate of 39 percent for patients treated with VIRULIZIN, compared with 11 percent one-year historical survival for similarly advanced malignant melanoma patients.
Global Markets Direct's, 'Malignant Pleural Effusion - Pipeline Review, H1 2012', provides an overview of the Malignant Pleural Effusion therapeutic pipeline.
No marrow elements were present, and no mitoses or other features suggesting a malignant process were noted.
Bissell's group, for example has recently shown that antibodies blocking the function of certain integrins seem to transform malignant breast cells into normal mammary cells, a finding that suggests new anticancer strategies.