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histiocytosis
(redirected from malignant histiocytosis)

   Also found in: Dictionary/thesaurus, Medical, Legal, Wikipedia 0.01 sec.
histiocytosis [‚his·tē·ō‚sī′tō·səs]
(medicine)
Abnormal proliferation of histiocytes, especially in hematopoietic tissues.


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Histiocytic neoplasms of the lymphohematopoietic system have had various names including histiocytic lymphoma, malignant histiocytosis, histiocytic medullary reticulosis, reticulum sarcoma, and malignant histiocytosis.
[FIGURE OMITTED] Conclusions Patients with infection-associated HLH usually have persistent unexplained fever, cytopenia, lymphadenopathy, and, frequently, hepatosplenomegaly and coagulopathy, causing diagnostic difficulties with malignant histiocytosis or T-cell lymphoma (2).
[14,15] The ALK/NPM reciprocal transcripts have been found in several childhood ALCLs, previously diagnosed as malignant histiocytosis, which expressed multiple myelomonocytic markers, including CD13.
 
 
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