malignant

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malignant

1. Pathol (of a tumour) uncontrollable or resistant to therapy; rapidly spreading
2. History (in the English Civil War) a Parliamentarian term for a royalist

malignant

[mə′līg·nənt]
(cell and molecular biology)
Pertaining to cells that have undergone phenotypic transformation by oncogenes or protooncogenes.
(medicine)
Endangering the life or health of an individual.
Of or pertaining to the growth and proliferation of certain neoplasms which terminate in death if not checked by treatment.
References in periodicals archive ?
A spokesman for the North Korean Foreign Ministry issued a statement accusing Bush of committing ''such a very grave provocation as malignantly slandering the DPRK'' in his speech to Congress on Tuesday, the (North) Korean Central News Agency (KCNA) reported.
However, neither virus can malignantly transform an infected cell.
Suddenly the girl looks up, startled; the frame freezes; a man's voice picks up the count, reversing it, three-two-one; the freeze-frame cuts away to film of an atomic explosion, the mushroom cloud spreading malignantly across the screen.
The Palestinian issue is central to Middle East politics, and recently the Gulf and the Arab-Israeli conflict, as one commentator put it, have "never been so malignantly intertwined".
Devere Smith, who interviewed hundreds of Angelenos with a myriad of perspectives on the event - and then brought them to uncanny life on stage - helped point out just how malignantly deluded (or, conversely, essentially good-hearted) many of us were and pointed, vaguely, to a greater future understanding.
These T cell subsets act in concert to eliminate virally infected or malignantly transformed cells.
Miss Grandin looked up and scowled malignantly through her tears at this piece of levity, but Tchetchensky merely smiled with godlike forbearance, and continued in a weak voice, evidently determined that his last words should be something pretty good.
Selective killing of cancer cells by activation of human checkpoint kinase 2: This study demonstrated that activation of the human checkpoint kinase 2 biological pathway, without DNA damage, results in selective toxicity in multiple malignantly transformed cell lines but not in non-cancerous cells.
Boland's interest in JCV lies in the fact that, like the closely related SV40 virus, it has a transforming gene that encodes T antigen, which will induce chromosome instability in vitro and make normal cells behave malignantly.
He malignantly expanded his power, indirectly sacrificing one hundred million peoples' lives over the course of several decades.
He did, more malignantly than anyone on earth thought possible.