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Malpighi, Marcello
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Malpighi, Marcello (märchĕl`lō mälpē`gē), 1628–94, Italian anatomist. A pioneer in the use of the microscope, he made many valuable observations on the structure of plants and animals. He completed Harvey's theory of circulation by his observation of the movement of blood through capillaries and recorded this, as well as his work on the structure of the lung, in De pulmonibus (1661). He is noted also for his studies of the structure of glands and of the brain, spleen, liver, and kidneys; of the anatomy of the silkworm; of the embryology of the chick; and of plant tissues. Several anatomical parts bear his name, including a layer in the human skin and the excretory tubules in insects. He was professor at the Univ. of Bologna (1666–91).

Malpighi, Marcello

(born March 10, 1628, Crevalcore, near Bologna, Papal States—died Nov. 30, 1694, Rome) Italian physician and biologist. In 1661 he identified the pulmonary capillary network, proving William Harvey's theory on blood circulation. He discovered the taste buds and was the first to see red blood cells and realize that they gave blood its colour. He studied subdivisions of the liver, brain, spleen, kidneys, bone, and deeper skin layers (Malpighian layers), concluding that even the largest organs are composed of minute glands. Malpighi also studied insect larvae (especially the silkworm), chick embryology, and plant anatomy, seeing an analogy between plant and animal organization. He is regarded as the founder of microscopic anatomy and may be regarded as the first histologist.


Malpighi, Marcello 

Born Mar. 10, 1628, in Crevalcore; died Nov. 30, 1694, in Rome. Italian biologist and physician. Fellow of the Royal Society of London.

Malpighi studied at the University of Bologna, receiving his degree as M.D. there in 1653. He was a professor at the university from 1656 to 1691. Malpighi was one of the founders of plant and animal microscopic anatomy. Using a microscope that magnified up to 180 times, he studied plant anatomy, described the cellular structure of plants (although he did not understand its meaning), discovered the tracheae, established the presence of ascending and descending currents of matter, and discussed the role of leaves in the nutrition of plants. Malpighi described the lymphoid corpuscles of the spleen (Malpighian corpuscles); the renal glomeruli (Malpighian glomeruli); the excretory organs of Arachnida, Myriopoda, and Insecta (Malpighian tubules); the deep layer of the skin (Malpighian layer); blood cells; the alveoli of the lungs; and the taste buds of the tongue. He also discovered capillary circulation.

WORKS

Opera omnia, vols. 1-2. London, 1687.
Opera posthuma …. London, 1697.

REFERENCES

Lunkevich, V. V. Ot Geraklita do Darvina, 2nd ed., vol. 1. Moscow, 1960. Pages 352-67.
Cardini, M. La vita e l’opera di Marcello Malpighi. Rome [1927].

D. V. LEBEDEV



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To protect itself from the harmful effects of the sun''s ultraviolet rays, the Malpighian cells of the epidermis or outer skin release a dark brown pigment called melanin which either appears as a good tan or a crop of freckles.
What we observed was quite intriguing: in Celera, Cyp6g1 was expressed in the midgut, the Malpighian tubules and the fat body, the tissues 'traditionally' associated with the detoxification of xenobiotics.
Some scales were covered by a thinned epidermis comprised of scant goblet and malpighian cells.
 
 
 
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