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mandelic acid

   Also found in: Medical, Acronyms, Wikipedia 0.03 sec.
mandelic acid [man′del·ik ′as·əd]
(organic chemistry)
C6H5CHOHCOOH A white, crystalline compound, melting at 117-119°C, darkening upon exposure to light; used in organic synthesis.


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In the neurobehavioral reports, four different measures were used to quantify the level of exposure to styrene: a) concentration of styrene in inhaled air (personal monitors) given as a time-weighted average (TWA), b) concentration of styrene in urine, c) concentration of mandelic acid in urine as a fraction of creatinine in urine, and d) concentration of mandelic acid in urine.
Biofilms of several gram-negative organisms were reduced by exposure to mandelic acid plus lactic acid (33).
StO, formed from styrene by cytochrome P450 monooxygenases, is primarily detoxified by microsomal epoxide hydrolase to phenylethylene glycol, which is further metabolized to yield mandelic acid (MA) and phenylglyoxylic acid (PGA), the principal urinary metabolites.
 
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