It is also interesting to note that plasma LPS levels in nonpathogenic SIV infections of sooty mangabeys
and African green monkeys were found to be normal .
Basic research could look for the mechanisms involved, either in sooty mangabeys
, other animals, or in any humans known to tolerate a high HIV viral loads and remain healthy.
The distribution of western lowland gorillas and red-capped mangabeys
in Africa overlaps.
Simian immunodeficiency virus infection in free-ranging sooty mangabeys
(Cercocebus atys atys) from the Tai Forest, Cote d'Ivoire: implications for the origin of epidemic human immunodeficiency virus type 2.
Last year, the rare, reclusive monkey was classified as a mangabey
and named Lophocebus kipunji (SN: 5/21/05, p.
We also observed HIV/SIV cross-reactive antibodies in De Brazza monkeys (20%), Wolf's monkeys (12 %), black mangabeys
(3%), and Angola pied colobus (4%).
The authors hypothesise that these differences in pDC activity may explain the reduced NK cell activation, blunted SIV-specific CD8+ T cell responses and decreased immune activation seen in naturally infected sooty mangabeys
The monkey species, now called the highland mangabey
or Lophocebus kipunji, has turned up at locations in southern Tanzania 370 kilometers apart.
In two different studies, researchers at the University of Pennsylvania School of Medicine, with collaborators from University of Minnesota, the University of Toronto, and Emory University, used comparative genomics of SIV infection and focussed at sooty mangabeys
Gordon and colleagues have investigated immune events occurring after SIV infection in the gut of sooty mangabeys
SIV-infected sooty mangabeys
develop a high viral load that does not increase their risk for developing AIDS and the SIV virus is rarely transmitted from mothers to babies.
Similarly, PTLV-3s exhibit broad diversity among NHPs in the wild; currently, 3 subtypes have been suggested according to the geographic origin of the strains (17): East African STLV-3 subtype A includes STLV-3 (PH969) found in a baboon (Papio hamadryas) from Eritrea (18) and from captive gelada baboons (Theropithecus gelada) (19); West and Central African STLV-3 subtype B includes STLV-3 (CTO-604) and STLV-3 (CTO-602) found among mangabeys
(Cercocebus torquatus) from Cameroon (20) and STLV-3 (PPAF3) from baboons (P.