If Irene Coates had spent a tiny fraction of the time reading about manic-depressive
illness that she devoted to wallowing in Bloomsburiana, she might have sensed the thinness of her theory.
Only a patient could so exquisitely describe the roller-coaster life and the helplessness to control emotions that manic-depressive patients endure.
We are inviting readers who recognize some manic-depressive symptoms in family histories to help further research by sending in the questionnaire on page 4.
Bipolar I: Because manic-depressive patients suffer from different degrees of mania, psychiatrists classify the severe and heightened mania with swings to depression as bipolar I.
However, younger manic-depressives had significantly higher transliminality scores than did older manic-depressives (r = -.
Among the manic-depressives and schizophrenics, volunteers likewise had a mean level of transliminality higher than the nonvolunteers, but the differences were insignificant (there were few nonvolunteers, and significance would have been difficult to attain).
Considering first the manic-depressives (below the diagonal), all of their 34 correlations were positive, 29 of them significantly so.
The discovery of a defective gene that plays a role in manic-depressive illness should lead to the identification of biological mechanisms that contribute to the illness.
SAN FRANCISCO--(BUSINESS WIRE)--April 1, 1996--A genetic clue to the origins of manic-depressive illness is close at hand, according to a team headed by researchers from the University of California San Francisco and the University of Costa Rica.
Additional strengths of the UCSF/UCR study include the rigor of the genetic analysis and the use of strict diagnostic criteria to identify family members afflicted with manic-depressive disorder, Freimer said.
And one of the things that has been very nice is that - at least in some situations - I feel that there has been more public discussion about manic-depressive illness than there was before.
That's certainly true, and there are certain kinds of manic-depressive illness where you have generally more euphoria in our manias and certain within the illness itself in which you're more likely to respond to lithium.