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Mass defect

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.09 sec.
Mass defect

The difference between the mass of an atom and the sum of the masses of its individual components in the free (unbound) state. The mass of an atom is always less than the total mass of its constituent particles; this means, according to Albert Einstein's well-known formula, that an energy of E = mc2 has been released in the process of combination, where m is the difference between the total mass of the constituent particles and the mass of the atom, and c is the velocity of light. The mass defect, when expressed in energy units, is called the binding energy, a term which is perhaps more commonly used. See Nuclear binding energy



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Scientists at Target Discovery will use the company's patented mass defect technology, Isotope-Differentiated Binding Energy Shift Tags (IDBEST(TM)), to validate clinical protein biomarkers at the isoform level, using retrospective patient samples provided by M.
The first phase of the study involves validating protein isoform biomarkers using Target Discovery's patented mass defect technology.
0 software incorporates enhanced stability for instrument control and data acquisition with new functionality for more intelligent precursor ion selection in MS/MS, including proprietary Dynamic Background Subtraction capabilities and Mass Defect Triggered IDA.
 
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