matrix metalloproteinase


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matrix metalloproteinase

[¦mā·triks mə‚tal·ō′prō·tē·ə‚nās]
(biochemistry)
Any member of a family of at least 19 structurally related zinc-dependent neutral endopeptidases collectively capable of degrading essentially all components of extracellular matrix.
References in periodicals archive ?
The matrix metalloproteinases (MMPs) play an important role in the process of cardiac remodeling by regulating structural integrity of the extracellular matrix.
Mechanisms of activation of tissue procollagenase by matrix metalloproteinase 3 (stromelysin).
Matrix metalloproteinase activity causes VEGFR-2 cleavage and microvascular rarefaction in rat mesentery.
A single bout of exercise activates matrix metalloproteinase in human skeletal muscle.
Increased intranuclear matrix metalloproteinase activity in neurons interferes with oxidative DNA repair in focal cerebral ischemia," Journal of Neurochemistry, vol.
The qPCR measurements were used to evaluate the impact of elevated miR-375 expression on the mRNA expression of the commonly regulated proteases, kallikrein 6 (KLK6), kallikrein 10 (KLK10), and matrix metalloproteinase 9 (MMP9).
Diabetes mellitus enhances vascular matrix metalloproteinase activity: role of oxidative stress.
Matrix metalloproteinase-2, membranous type 1 matrix metalloproteinase, and tissue inhibitor of metalloproteinase-2 expression in ectopic and eutopic endometrium.
Matrix metalloproteinase (MMP)-9 in cancer-associated fibroblasts (CAFs) is suppressed by omega-3 polyunsaturated fatty acids in vitro and in vivo.
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