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megacolon

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.03 sec.
megacolon [′meg·ə‚kō·lən]
(medicine)
Hypertrophy and dilation of the colon associated with prolonged constipation.


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difficile-associated disease (CDAD) is usually localized to the large bowel, where it manifests as diarrhea and pseudomembranous colitis, disease may progress to toxic megacolon, sepsis with or without intestinal perforation, and death (2) CDAD is increasingly recognized among residents of long-term care facilities (3) and even among persons living in the community (4); however, it most commonly affects patients in short-stay hospitals, where epidemic strains of C.
Never allowing irritant laxative use, as there is an increased risk of laxative habit, toxic megacolon and possibly GI cancer in long-term users of drugs such as Dulcolax, Ex-Lax, Per-Diem, Senokot and other irritant laxatives.
Considerable caution should be advised before OsmoPrep Tablets are used in patients with severe renal insufficiency, congestive heart failure, ascites, unstable angina, gastric retention, ileus, acute obstruction or pseudo-obstruction of the bowel, severe chronic constipation, bowel perforation, acute colitis, toxic megacolon, gastric bypass or stapling surgery, or hypomotility syndrome.
 
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